Revolutionize the Way​ You Handle Migraines and Headaches

The Revolutionary Treatment For Migraine And Headache. Migraines can stop you in your tracks, making even the simplest tasks feel daunting. But hold on, there’s hope! Regain control over your life with our migraine solution.

Plant-based polymers

Revolutionary Treatment

CGRP, interleukins and TNF-a to treat migraine

Emergency treatment

Supports Overall Good Health

Hypersensitivity

In migraine patients, the triggering threshold may be lower

Repeated stimulation can more easily reach the threshold at which the migraine cascade can be triggered.

 

Understanding the logic of the threshold: the goal is to act upstream, not just when the crisis is already established.

 

Clinical data

A long-term approach

MIGSPRAY is based on scientific and clinical development surrounding its local mode of action. Available results show its potential as a preventative measure, with a reduction in migraines reported in some users over several weeks.

4

publications and studies on the mechanism, effectiveness and use of MIGSPRAY
 

71%

of users with an observed reduction in migraines *

The available data are part of a progressive prevention approach: the assessment takes place over several weeks, with recognized criteria such as HIT-6 and MIDAS.

Publications

The 4 key studies

Fundamental

Migraine Model & TRPA1 Mechanism

Preclinical study on the parthenolide/salicin combination in a migraine model induced by dural application of an inflammatory mixture.

Shrivastava et al. Bread. 2026. DOI: 10.1097/j.pain.0000000000003789. PubMed: PMID 41512309.

Adult Clinic

Adult randomized trial vs placebo

Randomized, double-blind, placebo-controlled trial conducted over 12 weeks in adults with episodic migraine.

Shrivastava et al. Clinical Investigation. 2023;13(1):316-326. DOI: 10.37532/2041-6792.2023.13(1).316-326.

Children’s Clinic

Children and pregnant women

Randomized, double-blind, placebo-controlled study conducted over 90 days, with assessment of migraine frequency, MIDAS/HIT-6 scores and tolerance.

Shrivastava et al. Clinical Investigation. 2024. DOI: 10.54615/2231-7805.18063.

Real life

Real-world data

Real-life follow-up evaluating the use of MIGSPRAY over several months, with analysis of migraine frequency, intensity, duration and impact scores such as HIT-6 and MIDAS.

Shrivastava et al. Clinical Investigation. 2024. DOI: 10.54615/2231-7805.18064.

What the data says

Clinically evaluated efficacy

71%

  • MIGSPRAY’s clinical development is based on several evaluations of its mechanism and use.
  • Scientific collaboration The development of the product notably involved a collaboration with Inserm.
  • Recognized criteria The assessment is based on the MIDAS and HIT-6 questionnaires, references for measuring the impact of migraines on a daily basis.
  • Over several weeks, the benefits are observed over time, consistent with a logic of prevention.
  • Local action. Results obtained with a device with 100% mechanical action, without active substance diffused into the body.

* Adapted from Shrivastava et al., 2022. Results observed in a given population; they do not constitute a guarantee of individual results. MIGSPRAY does not claim to cure or stop migraines.

MIGSPRAY WORLDWIDE

Trusted by Thousands

Sam Delhi

Have been using it for a month now. I suffer from chronic migraine(almost everyday) for more than 12 years now. On Topaz medicine for more than 3 years but still no relief. No neurologists, allopathy, homeopathy or ayurvedic medicines so far helped with sudden attacks. Wanted to give this a shot, it’s working like wonders. I use it whenever I feel there is a chance of migraine trigger. Will try to review again after a few months.

Sandeep Chennai

Review TextGot instant relief from headaches and migraines with this amazing product. I use both the spray and roll-on, and they work wonders. Easy to use, no side effects, and highly effective. I have ve reduced my pill intake significantly. Perfect for office-goers and anyone prone to headaches. Highly recommend!

Payal New Delhi

Reduced My Migraine Pain "It helps me when I use it as soon as the migraine starts. Easy to carry and simple to use.

Binu Babu Mumbai

I bought this for my Niece who suffers with Horrible Migraine HA. So far the product is doing an excellent job keeping her from having Migraines. She uses it as soon as the Headache starts and the product stops it from advancing to a Migraine. Definitely Anyone with Migraine should try it.

Ramya Tamilnadu

My husband had migraine for the past 40 years and has a headache everyday, and needs painkillers daily of atleast 4-5. After using Mig Spray, there is a lot of difference, in the frequency and intensity of the pain as well. These have reduced.

Chandrapal singh panwar Madhya Pradesh

I can say that it miracle product. I suffered whole day due to migrain. I came in night & used it miracally in 5 min my migrain no more. Love this product

Rahul Goa

Perfect for Office Use "I keep it in my bag every day. It has reduced my need for painkiller tablets."

Real Stories. Real Relief.

See how MigSpray has helped people find comfort from migraine, headache, and sinus discomfort.

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MIGRAINE RELIEF ?

Ever wonder life comes to a standstill when Migraine takes over. In fact, it becomes almost impossible to carry on with your routine work, your plan and your day when Migraine kicks in. Well not anymore…!

Frequently Asked Questions

What is MIGSPRAY?

MIGSPRAY is a 15 ml nasal spray designed for the treatment and prevention of migraine and headache. It works locally on the nasal mucosa through a mechanical and osmotic action and is intended to help reduce the frequency and intensity of migraine episodes with regular use.

Yes. Migspray is intended for regular use as part of a daily migraine prevention routine. Apply 2 sprays in each nostril, 2–3 times a day, or as directed by your physician.

MIGSPRAY acts locally, mechanically, without releasing any active substance into the body: it is designed to be compatible with your usual treatments. If you have any doubts or are undergoing specific treatment, ask your doctor or pharmacist for confirmation.

Prevention works gradually. Allow approximately two months to begin to assess its effect on the frequency of your attacks, and up to three months for a complete course of treatment. Consistency is key.

MIGSPRAY is intended for adults and children above 12 years of age, with use by children supervised by an adult. Follow the appropriate directions and seek professional advice when needed.

A migraine nasal spray and a tablet work differently. MIGSPRAY acts locally on the nasal mucosa through a mechanical action and can be used alongside regular migraine treatments. It does not need to replace your prescribed migraine medication.

MIGSPRAY is designed specifically for migraine prevention and acts locally on the nasal mucosa. Its formulation creates a protective, film-forming layer with mechanical and osmotic action, helping reduce local exposure to factors involved in migraine sensitivity.

MIGSPRAY begins its local action after application, with the film acting on the nasal mucosa for several hours. Its migraine prevention benefits are designed to develop progressively with regular use over several weeks, so it should not be considered an instant migraine-stopping spray.

Yes. MIGSPRAY contains a combination of ingredients including glycerol, Salix alba, Curcuma longa, Vitis vinifera, Mentha piperita and other supporting ingredients. It uses a local mechanical approach rather than relying on a substance that is intended to circulate throughout the body.