Revolutionize the Way You Handle Migraines and Headaches
The Revolutionary Treatment For Migraine And Headache. Migraines can stop you in your tracks, making even the simplest tasks feel daunting. But hold on, there’s hope! Regain control over your life with our migraine solution.
Plant-based polymers
Revolutionary Treatment
CGRP, interleukins and TNF-a to treat migraine
Emergency treatment
Supports Overall Good Health
Hypersensitivity
In migraine patients, the triggering threshold may be lower
Repeated stimulation can more easily reach the threshold at which the migraine cascade can be triggered.

Understanding the logic of the threshold: the goal is to act upstream, not just when the crisis is already established.
Clinical data
A long-term approach
MIGSPRAY is based on scientific and clinical development surrounding its local mode of action. Available results show its potential as a preventative measure, with a reduction in migraines reported in some users over several weeks.
4
71%
The available data are part of a progressive prevention approach: the assessment takes place over several weeks, with recognized criteria such as HIT-6 and MIDAS.
Publications
The 4 key studies
Fundamental
Migraine Model & TRPA1 Mechanism
Preclinical study on the parthenolide/salicin combination in a migraine model induced by dural application of an inflammatory mixture.
Adult Clinic
Adult randomized trial vs placebo
Randomized, double-blind, placebo-controlled trial conducted over 12 weeks in adults with episodic migraine.
Children’s Clinic
Children and pregnant women
Randomized, double-blind, placebo-controlled study conducted over 90 days, with assessment of migraine frequency, MIDAS/HIT-6 scores and tolerance.
Real life
Real-world data
Real-life follow-up evaluating the use of MIGSPRAY over several months, with analysis of migraine frequency, intensity, duration and impact scores such as HIT-6 and MIDAS.
What the data says
Clinically evaluated efficacy
71%
- MIGSPRAY’s clinical development is based on several evaluations of its mechanism and use.
- Scientific collaboration The development of the product notably involved a collaboration with Inserm.
- Recognized criteria The assessment is based on the MIDAS and HIT-6 questionnaires, references for measuring the impact of migraines on a daily basis.
- Over several weeks, the benefits are observed over time, consistent with a logic of prevention.
- Local action. Results obtained with a device with 100% mechanical action, without active substance diffused into the body.
* Adapted from Shrivastava et al., 2022. Results observed in a given population; they do not constitute a guarantee of individual results. MIGSPRAY does not claim to cure or stop migraines.
MIGSPRAY WORLDWIDE





Trusted by Thousands

Have been using it for a month now. I suffer from chronic migraine(almost everyday) for more than 12 years now. On Topaz medicine for more than 3 years but still no relief. No neurologists, allopathy, homeopathy or ayurvedic medicines so far helped with sudden attacks. Wanted to give this a shot, it’s working like wonders. I use it whenever I feel there is a chance of migraine trigger. Will try to review again after a few months.

Review TextGot instant relief from headaches and migraines with this amazing product. I use both the spray and roll-on, and they work wonders. Easy to use, no side effects, and highly effective. I have ve reduced my pill intake significantly. Perfect for office-goers and anyone prone to headaches. Highly recommend!

Real Stories. Real Relief.
See how MigSpray has helped people find comfort from migraine, headache, and sinus discomfort.
Let's Talk
MIGRAINE RELIEF ?
Ever wonder life comes to a standstill when Migraine takes over. In fact, it becomes almost impossible to carry on with your routine work, your plan and your day when Migraine kicks in. Well not anymore…!
Frequently Asked Questions
What is MIGSPRAY?
MIGSPRAY is a 15 ml nasal spray designed for the treatment and prevention of migraine and headache. It works locally on the nasal mucosa through a mechanical and osmotic action and is intended to help reduce the frequency and intensity of migraine episodes with regular use.
Can I use a Migspray every day?
Yes. Migspray is intended for regular use as part of a daily migraine prevention routine. Apply 2 sprays in each nostril, 2–3 times a day, or as directed by your physician.
Can I take it with my current treatment?
MIGSPRAY acts locally, mechanically, without releasing any active substance into the body: it is designed to be compatible with your usual treatments. If you have any doubts or are undergoing specific treatment, ask your doctor or pharmacist for confirmation.
How long before you see an effect?
Prevention works gradually. Allow approximately two months to begin to assess its effect on the frequency of your attacks, and up to three months for a complete course of treatment. Consistency is key.
From what age? Can my child use it?
MIGSPRAY is intended for adults and children above 12 years of age, with use by children supervised by an adult. Follow the appropriate directions and seek professional advice when needed.
Is Migspray migraine nasal spray better than a tablet?
A migraine nasal spray and a tablet work differently. MIGSPRAY acts locally on the nasal mucosa through a mechanical action and can be used alongside regular migraine treatments. It does not need to replace your prescribed migraine medication.
What is the difference between a Migspray and a regular nasal spray?
MIGSPRAY is designed specifically for migraine prevention and acts locally on the nasal mucosa. Its formulation creates a protective, film-forming layer with mechanical and osmotic action, helping reduce local exposure to factors involved in migraine sensitivity.
How quickly does a Migspray work?
MIGSPRAY begins its local action after application, with the film acting on the nasal mucosa for several hours. Its migraine prevention benefits are designed to develop progressively with regular use over several weeks, so it should not be considered an instant migraine-stopping spray.
Is Migspray natural?
Yes. MIGSPRAY contains a combination of ingredients including glycerol, Salix alba, Curcuma longa, Vitis vinifera, Mentha piperita and other supporting ingredients. It uses a local mechanical approach rather than relying on a substance that is intended to circulate throughout the body.













